INVITED PERSPECTIVE FOR: “Near-infrared diffuse optical imaging ifor early prediction of breast cancer response to neoadjuvant chemotherapy: a comparative study using FDG-PET/CT”

INVITED PERSPECTIVE FOR: “Near-infrared diffuse optical imaging ifor early prediction of breast cancer response to neoadjuvant chemotherapy: a comparative study using FDG-PET/CT” Editorial comment:

Predictive ability of 18F-fluorodeoxyglucose positron emission tomography/computed tomography for pathological complete response and prognosis after neoadjuvant chemotherapy in triple-negative breast cancer patients

Objective The mortality of patients with locally advanced triple-negative breast cancer (TNBC) is high, and pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) is associated with improved prognosis. This retrospective study was designed and powered to investigate the ability of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) to predict pat...

Exploratory analysis of using supervised machine learning in [18F] FDG PET/CT images to predict treatment response in patients with metastatic and recurrent Brest tumors

Aim: Despite grate progress in treatments, breast cancer is still the most common invasive cancer and the most cause of cancer related death in women. Treatment could be improved and perhaps standardized if more reliable markers for tumour progression and poor prognosis could be developed. The aim of this study was to evaluate whether patient-based machine learning (ML) driven ...

The potential value of F-18 FDG PET in comparison to ct in early prediction of response to Imatinib (STI571) therapy in patients with gastrointestinal stromal tumors

  Introduction: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract. GIST has been shown to over-express c-KIT (CD117), the receptor tyrosine kinase. Imatinib (STI571 or Glivec) is a new type of tyrosine kinase inhibitor that selectively inhibits various tyrosine kinases and has been successfully used to trea...

FDG-PET/CT imaging predicts histopathologic treatment responses after the initial cycle of neoadjuvant chemotherapy in high-grade soft-tissue sarcomas.

PURPOSE In patients with soft-tissue sarcoma (STS), the early assessment of treatment responses is important. Using positron emission tomography/computed tomography (PET/CT) with [(18)F]fluorodeoxyglucose (FDG), we determined whether changes in tumor FDG uptake predict histopathologic treatment responses in high-grade STS after the initial cycle of neoadjuvant chemotherapy. EXPERIMENTAL DESIG...